potassium chloride iv compatibility
The opacity will diminish gradually. It is found in low concentration in plasma and extracellular fluids (3.5 to 5.0 mEq/liter in a healthy adult). Because many drugs are excreted in human milk, caution should be exercised when Potassium Chloride in Sodium Chloride Injection, USP is administered to a nursing mother. Pregnancy Category C. Animal reproduction studies have not been conducted with Potassium Chloride in Sodium Chloride Injection, USP. Tear outer wrap at notch and remove solution container. Squeeze and release drip chamber to establish proper fluid level in chamber. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. Avoid excessive heat. It is capable of inducing diuresis depending on the clinical condition of the patient. It is unlikely that these minor losses will lead to clinically significant changes within the expiration period. Chemical phlebitis and venospasm have also been reported. of the injection. USUAL DOSAGE: SEE INSERT. Senior Information Pharmacist, Welsh Medicines Information Centre. Close clamp. In patients with diminished renal function, administration of solutions containing sodium or potassium ions may result in sodium or potassium retention. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 30 Sep 2020) and others. ADDITIVES, USE ASEPTIC TECHNIQUE, MIX The flexible plastic container is fabricated from a specially formulated polyvinylchloride.

Dosage is dependent upon the age, weight and clinical IS UNDAMAGED. WATER FOR INJECTION. VIAFLEX Plus Container. Please refer to the WARNINGS icumedical. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. drugs a-z list Refer to complete directions accompanying set.

CONNECTIONS. electrolyte concentrations, overhydration, congested states or pulmonary edema. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. You are encouraged to report negative side effects of prescription drugs to the FDA. However, the use of potassium chloride injection in pediatric patients to treat potassium deficiency states when oral replacement therapy is not feasible is referenced in the medical literature. It is recommended the product be stored at room temperature (25o C/77o F); brief exposure up to 40o C (104o F) does not adversely affect the product. Potassium Chloride in Sodium Chloride Injection, USP should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. Exposure to temperatures above 25°C/77°F during transport and storage will lead to minor losses in moisture content. During initial replacement it may be preferable to use premixed infusions that are glucose-free. How should intravenous (IV) potassium chloride be administered in adults? FDA Rev date: 5/1/2005. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Generic Name: potassium chloride, sodium chloride, calcium chloride, sodium lactate, and dextrose The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of such solutions. Potassium Chloride in Lactated Ringers and Dextrose, potassium chloride, sodium chloride, calcium chloride, sodium lactate, and dextrose monohydrate injection, solution, We comply with the HONcode standard for trustworthy health information -. Intravenous solution with potassium chloride (I.V. Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. This solution is for administration by intravenous infusion only. (See PRECAUTIONS.). Such use Potassium-containing solutions are intrinsically irritating to tissues. Protect from freezing. container before administration of the fluid from the secondary container is Consult with pharmacist, if available. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million. position.

USE ONLY IF SOLUTION IS CLEAR AND CONTAINER Dextrose, potassium chloride or Lactated Ringer’s Injection should be given to a pregnant woman only if clearly needed. Potassium-containing solutions should be used with caution in the presence of cardiac disease, particularly in digitalized patients or in the presence of renal disease. Available for Android and iOS devices. Electrolytes should be monitored to determine the need for further infusions and to avoid hyperkalaemia. All injections in VIAFLEX Plus plastic containers are intended for intravenous administration using sterile equipment. Studies with Potassium Chloride in Sodium Chloride Injection, USP have not been performed to evaluate carcinogenic potential, mutagenic potential or effects on fertility. DIHYDRATE 20 mg; DEXTROSE, HYDROUS 5 g IN and discoloration prior to administration whenever solution and container permit. MAY CONTAIN HCl FOR CONSULT WITH compatible via Y site injection with hydrocortisone, potassium chloride, and vitamin B complex with C diltiazem compatible via Y-site with amiodarone, ampicillin, calcium

R x only. Caution must be exercised in the administration of Potassium Chloride in Sodium Chloride Injection, USP to patients receiving corticosteroids or corticotropin. High plasma concentrations of potassium may cause death through cardiac depression, arrhythmias or arrest. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Potassium administration via the intravenous route should only be used when the oral or enteral route is not available or will not achieve the required increase of serum potassium within a clinically acceptable time. peripheral and pulmonary edema is directly proportional to the electrolyte concentrations If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary. This is normal and does not affect the solution quality or safety. SINGLE-DOSE CONTAINER. The risk of dilutional states is inversely proportional to the electrolyte concentrations of the injection. Use gov.uk for the government response, and nhs.uk for health information. Plasma potassium levels are not necessarily indicative of tissue potassium levels. and PRECAUTIONS sections. If you need to know more you can ask one of our experts for help. Wherever possible commercially available ready to use diluted solutions should be prescribed and used. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies. Use of final filter is recommended during administration of all parenteral solutions, Warning: Do not use plastic containers in series connections. When smaller doses are required the unused portion should be discarded. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly.

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